| Cat. No. | Species | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|
| BA1-H5213 | Human | Human BACE-1 Protein, Tag Free (active enzyme, MALS verified) |  |
|
|
| BA1-H5261 | Human | Human BACE-1 Protein, Fc Tag |  |
|
|
| BA1-H5220 | Human | Human BACE-1 Protein, His Tag (active enzyme, MALS verified) |  |
|
Measured by its ability to cleave a fluorogenic peptide substrate, Mca-SEVNLDAEFRK(Dpn)RR-NH2. The specific activity is >3.5 pmol/min/µg, as measured under the described conditions (QC tested).
The purity of Human BACE-1, His Tag (Cat. No. BA1-H5220) is more than 95% and the molecular weight of this protein is around 55-65 kDa verified by SEC-MALS.
Measured by its ability to cleave a fluorogenic peptide substrate, Mca-SEVNLDAEFRK(Dpn)RR-NH2. The specific activity is >2.5 pmol/min/µg, as measured under the described conditions (QC tested).
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| TAK-070 | TAK-070 | Phase 1 Clinical | Takeda | Alzheimer Disease | Details |
| LY-2811376 | LY-2811376 | Eli Lilly And Company | Details | ||
| Verubecestat | MK-8931; SCH-900931; J1I0P6WT7T (UNII code) | Merck Sharp & Dohme Corp | Details | ||
| Lanabecestat | AZD-3293; LY-3314814 | Phase 3 Clinical | Astrazeneca Pharmaceutical Co Ltd | Alzheimer Disease | Details |
| LY-3202626 | LY-3202626 | Phase 2 Clinical | Eli Lilly And Company | Alzheimer Disease | Details |
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