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IL-22

IL-22 Molecule Information

Name:Interleukin-22
Target Synonym:MGC79384?IL-TIF?ZCYTO18?UNQ3099/PRO10096?ILTIF?Cytokine Zcyto18?IL-22?IL22?Interleukin 22?IL-10-Related T-Cell-Derived Inducible Factor?IL-10-Related T-Cell-Derived-Inducible Factor?Interleukin-22?TIFIL-23?IL-D110?IL-21?TIFa?MGC79382
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 1 Clinical

IL-22 Protein Product ListCompare or Buy

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Cat. No. Species Product Description Structure Purity Feature
IL2-H8247 Human Biotinylated Human IL-22 Protein, His,Avitag™
IL2-H8247-structure
IL2-H8247-sds
IL2-H8247-elisa_1
IL2-H524a Human Human IL-22 Protein, His Tag
IL2-H524a-structure
IL2-H524a-sds
IL2-H524a-elisa_1

IL-22 Part of Bioactivity data

IL2-H524a-ELISA
Human IL-22, His TagHuman IL-22, His Tag (Cat. No. IL2-H524a) ELISA bioactivity

Immobilized Human IL-22, His Tag (Cat. No. IL2-H524a) at 5 μg/mL (100 μL/well) can bind Anti-Human IL-22 MAb with a linear range of 0.5-16 ng/mL (QC tested).

IL2-H8247-ELISA
Biotinylated Human IL-22, His,Avitag™Biotinylated Human IL-22, His,Avitag™ (Cat. No. IL2-H8247) ELISA bioactivity

Immobilized Biotinylated Human IL-22, His,Avitag (Cat. No. IL2-H8247) at 1 μg/mL (100 μL/well)on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate. can bind Human IL-22 Antibody with a linear range of 0.1-4 ng/mL (QC tested).

IL-22 Molecule Synonym Name

IL-22,IL-TIF,ZCYTO18

IL-22 Molecule Background

Interleukin-22 (IL22) is also known as cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor (IL-TIF), which is belongs to the IL-10 family or IL-10 superfamily (including IL-19, IL-20, IL-24, and IL-26), a class of potent mediators of cellular inflammatory responses. IL-22 is produced by activated DC and T cells and initiates innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 biological activity is initiated by binding to a cell-surface complex composed of IL-22R1 and IL-10R2 receptor chains and further regulated by interactions with a soluble binding protein IL-22BP. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10.

IL-22 References

IL-22 Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
ARGX-112 LEO-138559; LP-0145; ARGX-112 Phase 1 Clinical Leo Pharma Inc, Argen-X Dermatitis, Atopic Details

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