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Kallikrein 3

Kallikrein 3 Molecule Synonym Name

KLK3,Kallikrein-3,APS,KLK2A1,PSA,Hk3,Seminin,Semenogelase

Kallikrein 3 Molecule Background

Kallikrein-3 (KLK3) is also known as Prostate-specific antigen (PSA), APS, Gamma-seminoprotein (Seminin), P-30 antigen, Semenogelase, is a glycoprotein enzyme, is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. The preferential cleavage site of KLK3 is ¡°-Tyr-|-Xaa-¡°, the catalytic activity is inhibited by SERPINA5 and is strongly inhibited by Zn2+. KLK3 hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.

Kallikrein 3 References

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