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Your Position: Home > LIF R


Brief Information

Target Synonym:CD_antigen=CD118;Oncostatin-M receptor subunit alpha;CD_antigen=CD130;IL-6R-beta;gp130;Interleukin-6 signal transducer;Membrane glycoprotein 130;IL-6R subunit beta;Leukemia inhibitory factor receptor;Interleukin-6 receptor subunit beta;LIFR;LIF-R;LIF rece
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase ?

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Cat. No. Species Product Description Structure Purity Feature
LIR-H4252 Human Human LIF R / CD118 Protein, Fc Tag

Part of Bioactivity data

Human LIF R, Fc TagHuman LIF R, Fc Tag (Cat. No. LIR-H4252) ELISA bioactivity

Immobilized ActiveMax® Human LIF, Tag Free (Cat. No. LIF-H521b) at 0.2 μg/mL (100 μL/well) can bind Human LIF R, Fc Tag (Cat. No. LIR-H4252) with a linear range of 4-125 ng/mL (QC tested).

Synonym Name



Leukemia inhibitory factor receptor is also known as LIFR; CD118; FLJ98106; FLJ99923; LIF-R; SJS2; STWS; SWS, is the receptor for leukemia inhibitory factor (LIF). The leukemia inhibitory factor is a polyfunctional cytokine that affects the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. LIF action appears to be mediated through a high-affinity receptor complex composed of a low-affinity LIF binding chain (LIF receptor) and a high-affinity converter subunit, gp130. Both LIFR and gp130 are members of a family of cytokine receptors that includes components of the receptors for the majority of hematopoietic cytokines and for cytokines that affect other systems, including the ciliary neurotrophic factor, growth hormone and prolactin Defects in LIFR are the cause of Stueve-Wiedemann syndrome (SWS), a severe autosomal recessive condition and belongs to the group of the bent-bone dysplasias.

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