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Your Position: Home > LILRB2

LILRB2

LILRB2 Molecule Information

Name:Leukocyte immunoglobulin-like receptor subfamily B member 2
Target Synonym:Myeloid Inhibitory Receptor 10?CD85d Antigen?ILT4?LIR2?CD85d?LIR-2?Leukocyte immunoglobulin-like receptor 2?CD85 antigen-like family member D?Immunoglobulin-like transcript 4?ILT-4?Monocyte/macrophage immunoglobulin-like receptor 10?MIR-10?CD_antigen: CD8

Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

LILRB2 Protein Product ListCompare or Buy

Product> Filter Results

Cat. No.	Species	Product Description
LI2-H82F5	Human	Biotinylated Human LILRB2 / CD85d / ILT4 Protein, Fc,Avitag™
CDD-H5259	Human	Human LILRB2 / CD85d / ILT4 Protein, Fc tag
LI2-H5220	Human	Human LILRB2 / CD85d / ILT4 Protein, His Tag

LILRB2 Molecule Synonym Name

LILRB2,ILT4,LIR2,MIR10,CD85d

LILRB2 Molecule Background

Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2) is also known as CD85 antigen-like family member D (CD85d), Immunoglobulin-like transcript 4 (ILT-4), Monocyte / macrophage immunoglobulin-like receptor 10 (MIR-10), which is a member of the the subfamily B class of LIR receptors. LILRB2 is receptor for class I MHC antigens. LILRB2 recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB2 competes with CD8A for binding to class I MHC antigens. LILRB2 / CD85d inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

LILRB2 References

LILRB2 Related Molecule

ANGPTL7

LILRB2 Clinical Drug Information

Name	Research Code	Research Phase	Company	Indications	Clinical Trials
MK-4830	MK-4830	Phase 2 Clinical	Merck Sharp & Dohme Corp	Carcinoma, Renal Cell; Carcinoma, Non-Small-Cell Lung	Details
JTX-8064	JTX-8064	Phase 1 Clinical	Jounce Therapeutics	Neoplasms	Details