0
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > LRP-10

LRP-10

LRP-10 Protein Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
LR0-H5259 Human Human LRP-10 Protein, Fc Tag
LR0-H5259-structure
LR0-H5259-sds

LRP-10 Molecule Synonym Name

LRP10,MSTP087,SP220,UNQ389,PRO724

LRP-10 Molecule Background

Low-density lipoprotein receptor-related protein 10 (LRP10), a member of the LDLR family, is a single-pass type I membrane protein, which contains two CUB domains and four LDL-receptor class A domains. As a probable receptor, LRP10 is involved in the internalization of lipophilic molecules or signal transduction. LRP10 may be involved in the uptake of lipoprotein APOE in liver. Furthermore, Deletion of the extracellular domain of LRP10 negated its inhibitory effect. It sugested that LRP10 may interfere with the formation of the beta-catenin/TCF complex and its binding to target DNA in the nucleus, and that the extracellular domain of LRP10 is critical for inhibition of the canonical Wnt/beta-catenin signaling pathway. LRP10 has been improved to play a significant role in the brain physiology other than lipoprotein metabolism.

LRP-10 References

This web search service is supported by Google Inc.

totop