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LYPD3 Molecule Information

Name:Ly6/PLAUR domain-containing protein 3
Target Synonym:GPI-anchored metastasis-associated protein C4.4A homolog;MIG-C4;Matrigel-induced gene C4 protein;LYPD3;C4.4A
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase ?

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Cat. No. Species Product Description Structure Purity Feature
LY3-H52H5 Human Human LYPD3 / C4.4A Protein, His Tag

LYPD3 Molecule Synonym Name


LYPD3 Molecule Background

Ly6/PLAUR domain-containing protein 3 (LYPD3) is also known as MIG-C4 ,C4.4A, GPI-anchored metastasis-associated protein C4.4A homolog and Matrigel-induced gene C4 protein,which is a cell membrane protein containing two UPAR/Ly6 domains. LYPD3 is expressed in placenta, skin and urothelium. LYPD3 is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. LYPD3 play a role in supporting cell migration and it is not only probably involved in urothelial cell-matrix interactions, but also in tumor progression.

LYPD3 References

LYPD3 Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Lupartumab amadotin BAY-1129980,BAY1129980 Phase Ⅰ Bayer Solid tumours Details

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