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NKp46

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Part of Bioactivity data

NC1-C5255-ELISA
Cynomolgus NKp46, Llama IgG2b Fc TagCynomolgus NKp46, Llama IgG2b Fc Tag (Cat. No. NC1-C5255) ELISA bioactivity

Immobilized Cynomolgus NKp46, Llama IgG2b Fc Tag (Cat. No. NC1-C5255) at 1 μg/mL (100 μL/well) can bind Anti-NKp46, hIgG4 with a linear range of 0.4-6 ng/mL (QC tested).

NC1-C82E5-MALS-HPLC
Biotinylated Cynomolgus NKp46, His,Avitag (Cat. No. ) MALS images

The purity of Biotinylated Cynomolgus NKp46, His,Avitag(Cat. No. NC1-C82E5) was more than 85% and the molecular weight of this protein is around 35-45 kDa verified by SEC-MALS.

Bioactivity-ELISA
Biotinylated Cynomolgus NKp46, His,AvitagBiotinylated Cynomolgus NKp46, His,Avitag (Cat. No. NC1-C82E5) ELISA bioactivity

Immobilized Biotinylated Cynomolgus NKp46, His,Avitag (Cat. No. NC1-C82E5) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate, can bind Anti-NKp46 Antibody, Chimeric mAb, Human IgG4 with a linear range of 0.1-2 ng/mL (QC tested).

Synonym Name

NCR1,LY94,CD335,NK-p46,NKp46,hNKp46,NCR-1,LY-94

Background

Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

Clinical and Translational Updates

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