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Neuropilin-1

Neuropilin-1 Molecule Information

Name:Neuropilin-1
Target Synonym:VEGF165R?CD_antigen=CD304?NRP1?NRP ?Neuropilin-1?Vascular endothelial cell growth factor 165 receptor
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase ?

Neuropilin-1 Protein Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
NR1-M5254 Mouse Mouse Neuropilin-1 / NRP1 / CD304 Protein, Mouse IgG2a Fc Tag, low endotoxin
NR1-M5254-structure
NR1-M5254-sds
NR1-M5254-elisa_1
NR1-H82E3 Human Biotinylated Human Neuropilin-1 / NRP1 / CD304 Protein, His Tag & Avi Tag (Avitag™)
NR1-H82E3-structure
NR1-H82E3-sds
NR1-H82E3-elisa_1
NR1-H5252 Human Human Neuropilin-1 / NRP1 / CD304 Protein, Fc Tag
NR1-H5252-structure
NR1-H5252-sds
NR1-H5252-elisa_1
NR1-H5228 Human Human Neuropilin-1 / NRP1 / CD304 Protein
NR1-H5228-structure
NR1-H5228-sds
NR1-H5228-elisa_1

Neuropilin-1 Molecule Synonym Name

NRP1,Neuropilin-1,NRP,VEGF165R,CD304

Neuropilin-1 Molecule Background

Neuropilin-1 (NRP1) is also known as Vascular endothelial cell growth factor 165 receptor (VEGF165R), CD antigen CD304, which belongs to the neuropilin family. The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells.

Neuropilin-1 References

Neuropilin-1 Related Molecule

Neuropilin-1 Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Vesencumab Anti-NRP1; M-1685-A; MNRP-1685-A; R-7347; RG-7347 Phase Ⅰ Genentech Solid tumours Details

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