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PROCR

Brief Information

Name:Endothelial protein C receptor
Target Synonym:Endothelial cell protein C receptor;Activated protein C receptor;APC receptor;EPCR;PROCR;CD201
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase ?

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Cat. No. Species Product Description Structure Purity Feature
PRR-H5254 Human Human PROCR / EPCR / CD201 Protein, Fc Tag
PRR-H5254-structure
PRR-H5254-sds

Synonym Name

PROCR,EPCR,CD201,APC receptor,CCCA,CCD41

Background

Endothelial protein C receptor (PROCR) is also known as Activated protein C receptor (APC receptor), Endothelial cell protein C receptor, CD antigen CD201. PROCR / EPCR / CD201 is a N-glycosylated protein, with a soluble form exists. PROCR is probably released by a metalloprotease. PROCR seems to have the same activity as the membrane-bound form. PROCR / EPCR / CD201 is expressed strongly in the endothelial cells of arteries and veins in heart and lung. PROCR binds activated protein C and enhances protein C activation by the thrombin - thrombomodulin complex. PROCR plays a role in the protein C pathway controlling blood coagulation.

Clinical and Translational Updates

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