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S100A14

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Cat. No. Species Product Description Structure Purity Feature
S14-H5121 Human Human S100A14 Protein, His Tag
S14-H5121-structure
S14-H5121-sds

S100A14 Molecule Synonym Name

S100A14,S114,S100A15

S100A14 Molecule Background

Protein S100-A14 (S100A14) is also known as S100 calcium-binding protein A14 (S114),which belongs to the S-100 family, containing one EF-hand domain.S100A14 is a homodimer can interact with AGER. S100A14 can modulate P53/TP53 protein levels, and play a role in the regulation of cell survival and apoptosis at different concentrations via receptor for advanced glycation end products (RAGE).S100A14 also plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53.

S100A14 References

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