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Siglec-5

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Cat. No. Species Product Description Structure Purity Feature
SI5-H5250 Human Human Siglec-5 / CD170 Protein, Fc Tag
SI5-H5250-structure
SI5-H5250-sds

Synonym Name

SIGLEC5,OB-BP2,CD170,CD33L2

Background

Sialic acid-binding Ig-like lectin 5 (SIGLEC5) is also known as CD33 antigen-like 2 (CD33L2), Obesity-binding protein 2 (OB-BP2), CD antigen CD170, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC5 / CD170 is expressed by monocytic / myeloid lineage cells. SIGLEC-5 / CD33-L2 binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

Clinical and Translational Updates

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