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TDGF1 Molecule Information

Name:Teratocarcinoma-derived growth factor 1
Target Synonym:CRGF;CRIPTO;Cripto-1 growth factor;TDGF1;Epidermal growth factor-like cripto protein CR1
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase ?

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Cat. No. Species Product Description Structure Purity Feature
CRO-H5253 Human Human TDGF1 / Cripto Protein, Fc Tag

TDGF1 Molecule Synonym Name


TDGF1 Molecule Background

Teratocarcinoma-derived growth factor 1 (TDGF1) is also known as Cripto-1 growth factor (CRGF), Epidermal growth factor-like cripto protein CR1, CRIPTO, is a cell membrane which contains one EGF-like domain. TDGF1 is preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts. TDGF1 interacts with the activin type-1 receptor ACVR1B. TDGF1 could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.

TDGF1 References

TDGF1 Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
BIIB-015 BIIB-015 Phase Ⅰ Biogen Solid tumours Details

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