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Your Position: Home > Carbonic Anhydrase IV

Carbonic Anhydrase IV

Brief Information

Name:Carbonic anhydrase IV
Target Synonym:Carbonate dehydratase IV,CA4,Carbonic Anhydrase 4,CA-IV,Retinitis Pigmentosa 17 (Autosomal Dominant),Carbonic Dehydratase IV,EC 4.2.1.1,CAIV,Car4,RP17,Carbonic anhydrase IV,EC:4.2.1.1
Number of Launched Drugs:3
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Approved

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Synonym Name

CA4,Carbonic anhydrase 4

Background

Carbonic anhydrase 4 (CA4) is also known as Carbonate dehydratase IV, Carbonic anhydrase IV, which belongs to the alpha-carbonic anhydrase family. CA4 may stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid. The enzyme regulation is activated by histamine, L-adrenaline, D-phenylalanine, L- and D-histidine. CA4 can interacts with SLC4A4.

Clinical and Translational Updates

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