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Your Position: Home > DR6

DR6

Brief Information

Name:Tumor necrosis factor receptor superfamily member 21
Target Synonym:CD358,Death receptor 6,Tumor Necrosis Factor Receptor Superfamily, Member 21,TNFR-Related Death Receptor 6,DR6,CD358 Antigen,TNF Receptor Superfamily Member 21,BM-018
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Pending

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Cat. No. Species Product Description Structure Purity Feature
TN1-H5252 Human Human DR6 / TNFRSF21 Protein, Fc Tag
TN1-H5252-structure
TN1-H5252-sds

also known as death receptor 6 (DR6), which is a member of the TNF-receptor superfamily. TNFRSF21 contains one death domain and four TNFR-Cys repeats. TNFRSF21 / DR6 has been shown to activate NF-¦ÊB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors.

Clinical and Translational Updates

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