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DR6

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Cat. No. Species Product Description Structure Purity Feature
TN1-H5252 Human Human DR6 / TNFRSF21 Protein, Fc Tag
TN1-H5252-structure
TN1-H5252-sds

also known as death receptor 6 (DR6), which is a member of the TNF-receptor superfamily. TNFRSF21 contains one death domain and four TNFR-Cys repeats. TNFRSF21 / DR6 has been shown to activate NF-¦ÊB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors.

DR6 References

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