Acrobiosystems for English
icon_bulk_orderBulk inquiry/Quick order
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > TREM-1


Brief Information

Name:Triggering receptor expressed on myeloid cells 1
Target Synonym:Triggering Receptor Expressed On Myeloid Cells 1,CD354 Antigen,Triggering Receptor Expressed on Myeloid Cells-1,TREM-1,TREM1,CD354,Triggering receptor expressed on monocytes 1
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:4
Lastest Research Phase:Phase 2 Clinical

Product ListCompare or Buy

By Product Status:
By Product Category:
By Species:
By Tag:
By Conjugate:
Cat. No. Species Product Description Structure Purity Feature
TR1-H5251 Human Human TREM-1 / CD354 Protein, Fc Tag
ACRO Quality

Synonym Name



Triggering receptor expressed on myeloid cells 1 (TREM1) is also known as CD antigen CD354, and is a type I transmembrane protein with a single Ig-like domain. TREM1 is highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. TREM-1 / CD354 stimulates neutrophil and monocyte-mediated inflammatory responses, and also triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. TREM1 can interacts with TYROBP / DAP12.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Nangibotide LR-12 Phase 2 Clinical Inotrem Shock, Septic; Coronavirus Disease 2019 (COVID-19) Details
CEL383 CEL-383 Phase 1 Clinical Celsius Therapeutics Inc Inflammatory Bowel Diseases Details
TREM 1 antibody(Boehringer Ingelheim International Gmbh) TREM 1 antibody(Boehringer Ingelheim International Gmbh) Phase 1 Clinical Boehringer Ingelheim International Gmbh Immune System Diseases Details
PY-159 PY-159 Phase 1 Clinical Centre for the Commercialization of Antibodies and Biologics Solid tumours; Neoplasms Details

This web search service is supported by Google Inc.

Call us
Call us
North America:
+1 800-810-0816 (Toll Free)
Asia & Pacific:
+86 400-682-2521
+1 888-377-6111
1 Innovation Way, Newark, DE 19711, USA

Leave a message