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Your Position: Home > BMP-4

BMP-4

Brief Information

Name:Bone morphogenetic protein 4
Target Synonym:BMP-4,Bone morphogenetic protein 2B,BMP-2B,BMP2B,DVR4
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Preclinical

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Cat. No. Species Product Description Structure Purity Feature
GMP-BM4H36 Human GMP Human BMP-4 / BMP2B Protein
GMP-BM4H36-structure
GMP-BM4H18 Human GMP Human BMP-4 / BMP2B (improved sequence) Protein
GMP-BM4H18-sds
BM4-H5317 Human Human BMP-4 / BMP2B Protein, premium grade
BM4-H5317-structure
BM4-H5317-sds
BM4-H5118 Human Human BMP-4 / BMP2B (improved sequence) Protein, premium grade
BM4-H5118-sds
ACRO Quality

Part of Bioactivity data

GMP-BM4H18-Cell-based assay
BMP-4 CELL

GMP Human BMP-4 (improved sequence) Protein (Cat. No. GMP-BM4H18) stimulates Human BMP (Luc) HEK293 Reporter Cell. The specific activity of GMP Human BMP-4 (improved sequence) Protein is > 1.90 x 10^3 U/mg (QC tested).

Protocol
BM4-H5317-Cell-based assay
BMP-4 CELL

Human BMP-4 Protein, premium grade (Cat. No. BM4-H5317) stimulates Human BMP (Luc) HEK293 Reporter cell. The EC50 value of this effect is 4.30 ng/mL (Routinely tested).

Protocol

Synonym Name

BMP4,BMP2B,BMP2B1,MCOPS6,OFC11,ZYME

Background

Bone Morphogenetic Protein 4 (BMP4) is a member of growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. BMP-4 Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2. BMP-4 can acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction.

Clinical and Translational Updates

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