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EMMPRIN

EMMPRIN Molecule Information

Name:Basigin
Target Synonym:Extracellular matrix metalloproteinase inducer,UNQ6505/PRO21383,Basigin (Ok Blood Group),Tumor Cell-Derived Collagenase Stimulatory Factor,Leukocyte Activation Antigen M6,Collagenase Stimulatory Factor,Basigin,5F7,Ok Blood Group,CD147 Antigen,EMPRIN,CD147
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:3
Lastest Research Phase:Approved

EMMPRIN Protein Product ListCompare or Buy

EMMPRIN Part of Bioactivity data

CD7-H82E0-ELISA
Biotinylated Human EMMPRIN, Avitag,His TagBiotinylated Human EMMPRIN, Avitag,His Tag (Cat. No. CD7-H82E0) ELISA bioactivity

Immobilized Biotinylated Human EMMPRIN, Avitag,His Tag (Cat. No. CD7-H82E0) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Anti-EMMPRIN Antibody, Mouse IgG1 with a linear range of 0.1-4 ng/mL (QC tested).

CD7-H82E0-MALS-HPLC
Biotinylated Human EMMPRIN, Avitag,His Tag (Cat. No. ) MALS images

The purity of Biotinylated Human EMMPRIN, Avitag,His Tag(Cat. No. CD7-H82E0) was more than 90% and the molecular weight of this protein is around 25-35 kDa verified by SEC-MALS.

Bioactivity-ELISA
Biotinylated Human EMMPRIN, Avitag,His TagBiotinylated Human EMMPRIN, Avitag,His Tag (Cat. No. CD7-H82E0) ELISA bioactivity

Immobilized Biotinylated Human EMMPRIN, Avitag,His Tag (Cat. No. CD7-H82E0) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Anti-EMMPRIN Antibody, Mouse IgG1 with a linear range of 0.1-4 ng/mL (QC tested).

EMMPRIN Molecule Synonym Name

Basigin,BSG,5F7,CD147,EMMPRIN,M6,OK,TCSF

EMMPRIN Molecule Background

CD147, also known as Basigin (BSG), or extracellular matrix metalloproteinase inducer (EMMPRIN). The human basigin protein contains 269 amino acids that form two heavily glycosylated C2 type immunoglobulin-like domains at the N-terminal extracellular portion. A second form of basigin has also been characterized that contains one additional immunoglobulin-like domain in its extracellular portion. As members of the immunoglobulin superfamily play fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development, basigin is thought also to play a role in intercellular recognition and regulate several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. Basigin is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins.

EMMPRIN References

EMMPRIN Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Iodine[131I] Metuximab Approved Chengdu Huasun Biotechnology Co Ltd 利卡汀, Licartin Mainland China Carcinoma, Hepatocellular s:35:"Chengdu Huasun Biotechnology Co Ltd"; 2006-10-12 Carcinoma, Hepatocellular Details

EMMPRIN Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Meplazumab HI6H8 Phase 3 Clinical Jiangsu Pacific-Meinuoke Bio-Pharmaceutical Co Ltd, The Fourth Military Medical University Malaria; Coronavirus Disease 2019 (COVID-19) Details
Anti-CD147 CAR T cell therapy (Xijing Hospital) Phase 1 Clinical Xijing Hospital Glioblastoma Details
Mertuzumab Phase 1 Clinical Jiangsu Pacific-Meinuoke Bio-Pharmaceutical Co Ltd, The Fourth Military Medical University Carcinoma, Non-Small-Cell Lung Details

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