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EDIL3

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Cat. No. Species Product Description Structure Purity Feature
ED3-H5259 Human Human EDIL3 Protein, Fc Tag
ED3-H5259-structure

Synonym Name

DEL1,EDIL3

Background

EDIL3, also known as Del1, is a novel extracellular matrix protein encoding three Notch-like epidermal growth factor repeats, an RGD motif, and two discoidin domains. EDIL3 is expressed in an endothelial cell-restricted pattern during early development. EDIL3 might involves autocrine angiogenic pathway for the embryonic endothelium, and this function is mediated in part by productive ligation of integrin alpha V beta 3. Overall, EDIL3 plays an important role in mediating angiogenesis and may be important in vessel wall remodeling and development. Moreover, It also influences endothelial cell behavior.

Clinical and Translational Updates

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