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EDIL3

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Cat. No.	Species	Product Description	Structure	Purity	Feature
ED3-H5259	Human	Human EDIL3 Protein, Fc Tag

ACRO Quality

Part of Bioactivity data

ED3-H5259-SPR

EDIL3 SPR

Human EDIL3, Fc Tag (Cat. No. ED3-H5259) immobilized on CM5 Chip can bind Human ITGAV&ITGB3 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT3-H52E3) with an affinity constant of 38.9 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

ED3-H5259-BLI

EDIL3 BLI

Loaded Human EDIL3, Fc Tag (Cat. No. ED3-H5259) on Protein A Biosensor, can bind Human ITGAV&ITGB3 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT3-H52E3) with an affinity constant of 533 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Synonym Name

DEL1,EDIL3

Background

EDIL3, also known as Del1, is a novel extracellular matrix protein encoding three Notch-like epidermal growth factor repeats, an RGD motif, and two discoidin domains. EDIL3 is expressed in an endothelial cell-restricted pattern during early development. EDIL3 might involves autocrine angiogenic pathway for the embryonic endothelium, and this function is mediated in part by productive ligation of integrin alpha V beta 3. Overall, EDIL3 plays an important role in mediating angiogenesis and may be important in vessel wall remodeling and development. Moreover, It also influences endothelial cell behavior.

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