0
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > CD27

CD27

CD27 Molecule Information

Name:CD27 antigen
Target Synonym:T-cell activation antigen CD27;T14;Tumor necrosis factor receptor superfamily member 7;CD27L receptor;CD27;TNFRSF7
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:3
Lastest Research Phase:Phase ?

CD27 Part of Bioactivity data

CD7-H5257-Cell-based assay
Human FcRn Heterodimer Protein Cell_Base

Flow Cytometry assay shows that Human CD27, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. CD7-H5257) can bind to Raji cells Surface Human CD70. The concentration of CD27 used is 10 μg/mL (Routinely tested).

TN7-H82F6-Cell-based assay
Human FcRn Heterodimer Protein Cell_Base

Flow Cytometry assay shows that Biotinylated Human CD27, Fc,Avitag (Cat. No. TN7-H82F6) can bind to Raji cells Surface Human CD70. The concentration of CD27 used is 10 μg/mL (Routinely tested).

CD7-H522b-ELISA
Human CD27, His TagHuman CD27, His Tag (Cat. No. CD7-H522b) ELISA bioactivity

Immobilized Human CD27, His Tag (Cat. No. CD7-H522b) at 2 μg/mL (100 μL/well) can bind Biotinylated Human CD27 Ligand, Avitag,Fc Tag (Cat. No. TN7-H82F4) with a linear range of 2-31 ng/mL (QC tested).

2B4-H82E9-ELISA
Biotinylated Human 2B4, Avitag,His Tag (recommended for biopanning)Biotinylated Human 2B4, Avitag,His Tag (recommended for biopanning) (Cat. No. 2B4-H82E9) ELISA bioactivity

Immobilized Biotinylated Human 2B4, Avitag,His Tag (recommended for biopanning) (Cat. No. 2B4-H82E9) at 1 μg/mL (100 μL/well) on streptavidin precoated (0.2 μg/well) plate, can bind Human CD48, Fc Tag (Cat. No. BC1-H5255) with a linear range of 0.3-5 ng/mL (QC tested).

CD27 Protein Product ListCompare or Buy

CD27 Molecule Synonym Name

CD27,TNFRSF7,S152,T14,Tp55

CD27 Molecule Background

CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-¦ÊB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.

CD27 References

CD27 Related Molecule

CD27 Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
MK-5890 MK-5890 Phase Ⅱ Merck Sharp & Dohme Non small cell lung cancer (NSCLC) Details
LOR-S03 CDX-527; LOR-A04; LOR-S01; LOR-S03 Preclinical Celldex Cancer Details
Anti-CD27 monoclonal antibody (Aduro Biotech) BION-1402 Phase Ⅰ Aduro BioTech, Merck Sharp & Dohme Solid tumours Details
Varlilumab CDX-1127 Phase Ⅱ Celldex, Cascadian Therapeutics, University of Virginia Solid tumours, Non-Hodgkin's lymphoma (NHL), Glioblastoma, Melanoma Details

This web search service is supported by Google Inc.

totop