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CD27

CD27 Molecule Information

Name:CD27 antigen
Target Synonym:T-cell activation antigen CD27?T14?Tumor necrosis factor receptor superfamily member 7?CD27L receptor?CD27?TNFRSF7
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase ?

CD27 Protein Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
CD7-H522b Human Human CD27 / TNFRSF7 Protein
CD7-H522b-structure
CD7-H522b-sds
CD7-H522b-elisa_1
CD7-M5252 Mouse Mouse CD27 / TNFRSF7 Protein, Mouse IgG2a Fc Tag, low endotoxin
CD7-M5252-structure
CD7-M5252-sds
CD7-M5252-elisa_1
CD7-H5257 Human Human CD27 / TNFRSF7 Protein, Mouse IgG2a Fc Tag, low endotoxin
CD7-H5257-structure
CD7-H5257-sds
CD7-H5257-elisa_1
CD7-C5259 Cynomolgus / Rhesus macaque Cynomolgus / Rhesus macaque CD27 / TNFRSF7 Protein, Mouse IgG2a Fc Tag, low endotoxin
CD7-C5259-structure
CD7-C5259-sds
CD7-C5259-elisa_1
TN7-H82F6 Human Biotinylated Human CD27 / TNFRSF7 Protein, Fc Tag, Avi Tag (Avitag™)
TN7-H82F6-structure
TN7-H82F6-sds
TN7-H82F6-elisa_1
CD7-H5254 Human Human CD27 / TNFRSF7 Protein, Fc Tag
CD7-H5254-structure
CD7-H5254-sds
CD7-H5254-elisa_1

CD27 Molecule Synonym Name

CD27,TNFRSF7,S152,T14,Tp55

CD27 Molecule Background

CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-¦ÊB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.

CD27 References

CD27 Related Molecule

CD27 Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Anti-CD27 monoclonal antibody (Aduro Biotech) BION-1402 Phase Ⅰ Aduro BioTech, Merck Sharp & Dohme Solid tumours Details
Varlilumab CDX-1127 Phase Ⅱ Celldex, Cascadian Therapeutics, University of Virginia Prostate cancer, hematological malignancies, Breast cancer, Solid tumours, Ovarian cancer, Renal carcinoma, Melanoma Details

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