0
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > CD27

CD27

CD27 Molecule Information

Name:CD27 antigen
Target Synonym:CD27 antigen,Tumor necrosis factor receptor superfamily member 7,CD27L receptor,CD27,CD27 Molecule,T-Cell Activation Antigen CD27,TNFRSF7,T14,T Cell Activation Antigen S152,S152. LPFS2,S152,Tp55,Tumor Necrosis Factor Receptor Superfamily, Member 7
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:4
Lastest Research Phase:Phase 2 Clinical

CD27 Protein Product ListCompare or Buy

CD27 Part of Bioactivity data

CD7-H5257-Cell-based assay
Human FcRn Heterodimer Protein Cell_Base

Flow Cytometry assay shows that Human CD27, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. CD7-H5257) can bind to Raji cells Surface Human CD70. The concentration of CD27 used is 10 μg/mL (Routinely tested).

TN7-H82F6-Cell-based assay
Human FcRn Heterodimer Protein Cell_Base

Flow Cytometry assay shows that Biotinylated Human CD27, Fc,Avitag (Cat. No. TN7-H82F6) can bind to Raji cells Surface Human CD70. The concentration of CD27 used is 10 μg/mL (Routinely tested).

CD7-M5252-ELISA
Mouse CD27, Mouse IgG2a Fc Tag, low endotoxinMouse CD27, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. CD7-M5252) ELISA bioactivity

Immobilized Mouse CD27, Mouse IgG2a Fc Tag (Cat. No. CD7-M5252) at 2 μg/mL (100 μL/well) can bind Biotinylated Mouse CD70, His Tag, Avi Tag with a linear range of 1-16 ng/mL (QC tested).

CD7-H522b-MALS-HPLC
Human CD27, His Tag (Cat. No. ) MALS images

The purity of Human CD27, His Tag (Cat. No. CD7-H522b) was more than 85% and the molecular weight of this protein is around 38-48 kDa verified by SEC-MALS.

Bioactivity-ELISA
Human CD27, His TagHuman CD27, His Tag (Cat. No. CD7-H522b) ELISA bioactivity

Immobilized Human CD27, His Tag (Cat. No. CD7-H522b) at 2 μg/mL (100 μL/well) can bind Biotinylated Human CD27 Ligand, Avitag,Fc Tag (Cat. No. TN7-H82F4) with a linear range of 2-31 ng/mL (QC tested).

CD27 Molecule Synonym Name

CD27,TNFRSF7,S152,T14,Tp55

CD27 Molecule Background

CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-¦ÊB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.

CD27 References

CD27 Related Molecule

CD27 Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Anti-CD27 monoclonal antibody (Aduro Biotech) BION-1402 Phase 1 Clinical Aduro Biotech Neoplasms Details
LOR-S03 CDX-527; LOR-A04; LOR-S01; LOR-S03 Phase 1 Clinical Celldex Liver Neoplasms; Ovarian Neoplasms; Head and Neck Neoplasms; Solid tumours; Carcinoma, Renal Cell; Esophageal Neoplasms; Stomach Neoplasms; Microsatellite instability-high cancer; Urinary Bladder Neoplasms; Cholangiocarcinoma; Breast Neoplasms; Peritoneal Neoplasms; Colorectal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Varlilumab CDX-1127 Phase 2 Clinical Celldex Urologic Diseases; Leukemia, Lymphocytic, Chronic, B-Cell; Melanoma; Carcinoma, Non-Small-Cell Lung; Urogenital Neoplasms; Lymphoma; Glioma; Lymphoma, Non-Hodgkin; Urologic Neoplasms; Lymphoma, Mantle-Cell; Prostatic Neoplasms; Ovarian Neoplasms; Urinary Bladder Neoplasms; Triple Negative Breast Neoplasms; Kidney Diseases; Glioblastoma; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Kidney Neoplasms; Head and Neck Neoplasms; Lymphoma, B-Cell Details
MK-5890 MK-5890 Phase 2 Clinical Merck & Co Inc Solid tumours; Triple Negative Breast Neoplasms; Carcinoma, Non-Small-Cell Lung Details

This web search service is supported by Google Inc.

totop