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CD300c

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Cat. No. Species Product Description Structure Purity Feature
CDC-H5224 Human Human CD300c / LMIR2 Protein, His Tag
CDC-H5224-structure
CDC-H5224-sds

Synonym Name

CD300C,CLM-6,CMRF35-A1,CMRF-35,CMRF35A,IGSF16

Background

CMRF35-like molecule 6 (CLM-6) is also known as CD300 antigen-like family member C, CMRF35-A1, Immunoglobulin superfamily member 16 (IgSF16) , CD antigen CD300c, which belongs to the CD300 family. CLM-6 contains one Ig-like V-type (immunoglobulin-like) domain. CD300a/c RNA and surface expression were downregulated after stimulation of plasmacytoid dendritic cells (pDCs) with TLR7 and TLR9 ligands. Exogenous interferon (IFN)-alpha down-regulated CD300a/c expression. CD300a and CD300c play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300a and CD300c are indistinguishable on the surface of NK cells.

Clinical and Translational Updates

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