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Your Position: Home > BTN1A1

BTN1A1

Brief Information

Name:Butyrophilin subfamily 1 member A1
Target Synonym:BT,BTN
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

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Cat. No. Species Product Description Structure Purity Feature
BT1-H82E6 Human Biotinylated Human BTN1A1 / Butyrophilin Protein, His,Avitag™
BT1-H82E6-structure
BT1-H82E6-sds
BT1-H5253 Human Human BTN1A1 / Butyrophilin Protein, Fc Tag
BT1-H5253-structure
BT1-H5253-sds
BT1-H5222 Human Human BTN1A1 / Butyrophilin Protein, His Tag
BT1-H5222-structure
BT1-H5222-sds
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Synonym Name

BTN1A1,Butyrophilin,BTN

Background

Butyrophilin subfamily 1 member A1 (BTN1A1) is also known as BTN, which is a member of the immunoglobulin superfamily and the major protein associated with fat droplets in the milk. BTN1A1 may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. Furthermore, BTN1A1 regulates the amount of lipids and size of droplets expressed in milk and inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Nelmastobart hSTC-810; STT 003; STT-003 Phase 2 Clinical STCube Pharmaceuticals Inc Solid tumours; Small Cell Lung Carcinoma Details

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