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IL-23R

IL-23R Protein Product ListCompare or Buy

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Cat. No. Species Product Description Structure Purity Feature
ILR-H82F3 Human Biotinylated Human IL-23 R Protein, Fc,Avitag™
ILR-H82F3-structure
ILR-H82F3-sds
ILR-H82F3-elisa_1
ILR-H5254 Human Human IL-23 R Protein, Fc Tag
ILR-H5254-structure
ILR-H5254-sds
ILR-H5254-elisa_1
ILR-H5254-elisa_2
ILR-H52H4 Human Human IL-23 R Protein, His Tag
ILR-H52H4-structure
ILR-H52H4-sds
ILR-H52H4-elisa_2
ILR-M5251 Mouse Mouse IL-23 R Protein, Fc Tag
ILR-M5251-structure
ILR-M5251-sds

IL-23R Molecule Synonym Name

IL-23 R,IL-23 Receptor

IL-23R Molecule Background

Interleukin 23 receptor (IL-23R) is a type I cytokine receptor, and IL-23R pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. Also, IL-23R associates constitutively with Janus kinase 2 (JAK2), and binds to transcription activator STAT3 in a ligand-dependent manner. Furthermore, IL-23R mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. As for IL-23, it may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.

IL-23R References

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