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Your Position: Home > TACI/TNFRSF13B

TACI/TNFRSF13B

TACI/TNFRSF13B Product List

Cat. No. Species Product Description Structure Purity Feature
TAI-H5256 Human Human TACI/TNFRSF13B Protein, Fc Tag
TAI-H5256-structure
TAI-H5256-sds
TAI-H5256-elisa_1

TACI/TNFRSF13B Molecule Synonym Name

CD267,TACI,TNFRSF13B

TACI/TNFRSF13B Molecule Background

Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B (TNFRSF13B). It was originally discovered because of its ability to interact with calcium-modulator and cyclophilin ligand (CAML). TACI was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family: BAFF and APRIL. The present study demonstrated that, in NSCLC, a proliferation-inducing ligand (APRIL), B-cell maturation antigen (BCMA)and transmembrane activator and CAML interactor (TACI) proteins are abnormally expressed by immunohistochemistry, reverse transcription-quantitative polymerase chain reaction and western blotting. In addition, the expression of APRIL, BCMA and TACI were observed to be involved in extracellular signal-regulated kinase (ERK)1/2 activation in A549 cells.

TACI/TNFRSF13B References

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