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B7-H7

B7-H7 Protein Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
B77-H5257 Human Human B7-H7 / HHLA2 Protein, Fc Tag
B77-H5257-structure
B77-H5257-sds
B77-H5257-elisa_1
B77-H52H5 Human Human B7-H7 / HHLA2 Protein, His Tag
B77-H52H5-structure
B77-H52H5-sds
B77-H52H5-elisa_1
B77-H82F5 Human Biotinylated Human B7-H7 / HHLA2 Protein, Fc Tag, Avi Tag (Avitag™)
B77-H82F5-structure
B77-H82F5-sds
B77-H82F5-elisa_1

B7-H7 Molecule Synonym Name

B7-H7,HHLA2,B7 Homolog 7

B7-H7 Molecule Background

B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members.

B7-H7 References

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