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LILRA6

LILRA6 Protein Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
LI6-H82E2 Human Biotinylated Human LILRA6 / CD85b / ILT8 Protein, His Tag, Avi Tag (Avitag™)
LI6-H82E2-structure
LI6-H82E2-sds
LI6-H82E2-elisa_1

LILRA6 Molecule Synonym Name

LILRA6,CD85b,ILT8,ILT-8

LILRA6 Molecule Background

The LILRs are a family of receptors that regulate the activities of myelomonocytic cells. LILRB3 and LILRA6 represent a pair of inhibitory/activating receptors with identical extracellular domains and unknown ligands. LILRB3 (ILT5) and LILRA6 (ILT8) are highly polymorphic receptors with similar extracellular domains. LILRA6 can signal through association with an activating adaptor molecule, FcR¦Ã, which bears a cytoplasmic tail with an immunoreceptor tyrosine-based activation motif. Analysis of mRNA expression in the major fractions of PBMCs showed that LILRA6 is primarily expressed in monocytes, and its expression level correlates with copy number of the gene.

LILRA6 References

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