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PVRIG Part of Bioactivity data

Human PVRIG, Fc TagHuman PVRIG, Fc Tag (Cat. No. PVG-H5257) ELISA bioactivity

Immobilized Human Nectin-2, His Tag (Cat. No. PV2-H52E2) at 5 μg/mL (100 μL/well) can bind Human PVRIG, Fc Tag (Cat. No. PVG-H5257) with a linear range of 2-31 ng/mL (QC tested).

Biotinylated Human PVRIG, His,AvitagBiotinylated Human PVRIG, His,Avitag (Cat. No. PVG-H82E3) ELISA bioactivity

Immobilized Biotinylated Human PVRIG, His,Avitag (Cat. No. PVG-H82E3) at 1 μg/mL (100 μL/well) on streptavidin precoated (0.5 μg/well) plate, can bind Human Nectin-2, Fc Tag (Cat. No. PV2-H5253) with a linear range of 0.1-5 ng/mL (QC tested).

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PVRIG Molecule Synonym Name

C7orf15,C7orf15MGC138295,CD112R,MGC104322,MGC138297,MGC2463,PVRIG,CD112 receptor

PVRIG Molecule Background

Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.

PVRIG References

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