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Your Position: Home > IL-3 R alpha

IL-3 R alpha

IL-3 R alpha Protein Product ListCompare or Buy

Product> Filter Results

Cat. No.	Species	Product Description
ILA-C52H3	Canine	Canine IL-3 R alpha / CD123 Protein, His Tag
ILA-H82H5	Human	Biotinylated Human IL-3 R alpha / CD123 Protein, His,Avitag™ (MALS verified)
ILA-HF2H9	Human	FITC-Labeled Human IL-3 R alpha / CD123 Protein, His Tag
ILA-M52H4	Mouse	Mouse IL-3 R alpha / CD123 Protein, His Tag (SPR verified)
ILA-C52H6	Cynomolgus	Cynomolgus IL-3 R alpha / CD123 Protein, His Tag (SPR verified)
ILA-H5255	Human	Human IL-3 R alpha / CD123 Protein, Llama IgG2b Fc Tag, low endotoxin
ILA-H52H6	Human	Human IL-3 R alpha / CD123 Protein, His Tag (SPR verified)

IL-3 R alpha Part of Bioactivity data

ILA-M52H4-SPR

Mouse IL-3 R alpha, His Tag (Cat. No. ILA-M52H4) captured on CM5 Chip via anti-His antibody can bind Mouse IL-3, Tag Free with an affinity constant of 0.704 μM as determined in SPR assay (Biacore T200) (QC tested).

Protocol

ILA-C52H6-SPR

Cynomolgus IL-3 R alpha, His Tag (SPR verified) (Cat. No. ILA-C52H6) captured on CM5 Chip via anti-His antibody can bind Human IL-3, Tag Free with an affinity constant of 0.271 μM as determined in SPR assay (Biacore 8k) (QC tested).

Protocol

IL-3 R alpha Molecule Synonym Name

IL3R,IL3RA,IL-3Ra,IL-3R-alpha,IL3RAY,IL3RX,IL3RY,CD123 antigen,CD123,hIL3Ra,hIL-3Ra,MGC34174,IL-3 R alpha

IL-3 R alpha Molecule Background

Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.