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LIGHT

LIGHT Protein Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
LIT-H82E5 Human Biotinylated Human LIGHT / TNFSF14 Protein, His Tag, Avi Tag (Avitag™)
LIT-H82E5-structure
LIT-H5256 Human Human LIGHT / TNFSF14 Protein, Mouse IgG2a Fc Tag, low endotoxin
LIT-H5256-structure
LIT-H5256-sds
LIT-H5256-elisa_1
LIT-H5247 Human Human LIGHT / TNFSF14 Protein, His Tag
LIT-H5247-structure
LIT-H5247-sds
LIT-H5247-elisa_1
LIT-H5265 Human Human LIGHT / TNFSF14 Protein, Fc tag
LIT-H5265-structure
LIT-H5265-sds
LIT-H5265-elisa_1

LIGHT Molecule Synonym Name

CD258 antigen, CD258, HVEM-L, LIGHT, LTg, TNFSF14, TR2, HVEML

LIGHT Molecule Background

Tumor necrosis factor ligand superfamily member 14(LIGHT) is a tumor necrosis factor (TNF) superfamily ligand that regulates T cell immune responses by signaling through the herpes virus entry mediator (HVEM) and the lymphotoxin beta receptor (LTbetaR). LIGHT has emerged as a potent initiator of T cell co-stimulation signals effecting CTL-mediated tumor rejection, allograft rejection and graft versus host disease. Constitutive expression of LIGHT leads to tissue destruction and autoimmune-like disease syndromes.

LIGHT References

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