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Explore our series of high-quality proteins covering comprehensive diagnostic indicators in order to facilitate the in vitro diagnostic research of neurological diseases.
Pre-formed fibrils are an invaluable preclinical model for exploring pathogenesis of neurological diseases through aggregation of misfolded proteins. Explore our pre-seeded PFFs to use in your research.
Neural factors are a class of protein molecules with neurotrophic activity that can promote the survival and regeneration of nerve cells. Explore our series of recombinant neural factors to support the culture and differentiation of nerve cells.
Partnering with Diagnostic Biochips, we now provide solutions for in vivo electrophysiology recordings, including high-quality multi-channel electrodes and other products to facilitate high-quality, efficient analysis of neural circuit structure and function.
Neural antibodies can specifically label and recognize molecules on nerve cells, enabling a more comprehensive understanding and study of the biological properties, functions, and mechanisms of nerve cells in neurodegenerative diseases.
Covering iPSC neural cells, brain organoids, and microelectrode array services, our tools support neural development, disease modeling, and drug screening with high quality and reliable performance to meet diverse research needs.
Protein markers are an essential component in biological research and drug development. Whether it is for protein electrophoresis or western blot, our pre-stained protein markers help you quickly determine the molecular weight of the target protein or evaluate the transfer efficiency.
Streptavidin is a tetrameric protein providing 4 high-affinity biotin binding sites. We offer a wide array of products pre-conjugated with streptavidin to support your research as well as biotinylated proteins.
Setting the corresponding isotype control antibody to detect non-specific binding can reduce the generation of false positive results and evaluate the possible influencing factors accurately in the drug development process. Explore our isotype controls for your research.
The efficacy of a therapeutic antibody depends on the Fab fragment and its binding activity to the target antigen, but also depends on the Fc fragment and its interaction with key Fc receptors.Therefore, candidates must be tested against a panel of receptors during antibody engineering. Explore our comprehensive collection of recombinant Fc receptor proteins!
We committed to accelerating the research, development, approval, and commercialization of infectious disease vaccines. With this idea, ViruStop is specially designed for virus research!
1e5 of Mouse Anti-CD3 antibody coupled beads (5.5μm) were stained with different concentration of Alexa Fluor 488-Labeled Human CD3 epsilon Protein, His Tag (Cat. No. CDE-HA2H3) and negative control protein respectively, AF488 signal was used to evaluate the binding activity (QC tested).
1e5 of Mouse Anti-CD3 antibody coupled beads (5.5μm) were stained with different concentration of Alexa Fluor 488-Labeled Human CD3 epsilon Protein, His Tag (Cat. No. CDE-HA2H3) and negative control protein respectively, AF488 signal was used to evaluate the binding activity (QC tested).
Bispecific T-cell Engager captured on Protein A Chip can bind Biotinylated Human CD3E, His Tag, primary amine labeling (Cat. No. CDE-H8224) with an affinity constant of 0.815 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).
Bispecific T-cell Engager captured on Protein A Chip can bind HRP-Human CD3 epsilon, His Tag (Cat. No. CDE-HR2H4) with an affinity constant of 4.45 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).
CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.
Clinical and Translational Updates
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