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Tau-441

Tau-441 Protein Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
TAU-H51H3 Human Human Tau-441 / 2N4R Protein, His Tag
TAU-H51H3-structure
TAU-H51H3-sds

Tau-441 Molecule Synonym Name

DDPAC,FTDP-17,MAPT,MSTD,MTBT1,Tau,PHF-tau,TAU

Tau-441 Molecule Background

Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies. Tau-441 is known as "2N4R," "Isoform Tau-F," "Tau-4" or "Tau 441", which consisting of 441 amino acid. Tau-441 is a potential therapeutic target for pathogenesis.

Tau-441 References

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