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Your Position: Home > CD44

CD44

CD44 Product List

Cat. No. Species Product Description Structure Purity Feature
CD4-H5226 Human Human CD44 Protein
CD4-H5226-structure
CD4-H5226-sds
PG1-H5255 Human Human CD44 Protein, Fc Tag (HPLC-verified)
PG1-H5255-structure
PG1-H5255-sds
PG1-H5255-hplc

CD44 Molecule Synonym Name

CD44,CDW44,CSPG8,ECMR-III,HCELL,HUTCH-I,IN,LHR,MC56,MDU2,MDU3,MIC4,Pgp1,Epican

CD44 Molecule Background

CD44 antigen is a cell-surface glycoprotein involved in cell¨Ccell interactions, cell adhesion and migration. CD44 is expressed in a large number of mammalian cell types. CD44 is a receptor for hyaluronic acid and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44 function is controlled by its posttranslational modifications. One critical modification involves discrete sialofucosylations rendering the selectin-binding glycoform of CD44 called HCELL (for Hematopoietic Cell E-selectin/L-selectin Ligand). CD44 participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms.

CD44 References

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