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Your Position: Home > DR3 / TNFRSF25

DR3 / TNFRSF25

Brief Information

Name:Tumor necrosis factor receptor superfamily member 25
Target Synonym:Apo-3,Apoptosis-inducing receptor AIR,Apoptosis-mediating receptor DR3,Apoptosis-mediating receptor TRAMP,Death receptor 3,Lymphocyte-associated receptor of death,Protein WSL,DDR3,Death Receptor Beta,TNFRSF12,TRAMP,DR3,WSL-1,PH Domain-Containing Family G
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 1 Clinical

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By Product Category:
By Conjugate:
Cat. No. Species Product Description Structure Purity Feature
TN5-H52H3 Human Human DR3 / TNFRSF25 Protein, His Tag
TN5-H52H3-structure
TN5-H52H3-sds
TN5-C5257 Cynomolgus Cynomolgus DR3 / TNFRSF25 Protein, Fc Tag
TN5-C5257-structure
TN5-C5257-sds
TN5-H5258 Human Human DR3 / TNFRSF25 Protein, Fc Tag
TN5-H5258-structure
TN5-H5258-sds

Synonym Name

TNFRSF25,DR3,APO3,DDR3,TNFRSF12,WSL,WSL1

Background

Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) is also known as Apo-3, Death receptor 3 (DDR3 or DR3), Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor TRAMP, Lymphocyte-associated receptor of death, Apo-3, which is a member of the TNF-receptor superfamily. TNFRSF25 is a homodimer protein, which can Interact strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. TNFRSF25 is receptor for TNFSF12 / APO3L / TWEAK.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
PTX-35 PTX-35 Phase 1 Clinical Heat Biologics Neoplasms Details
PTX-35 PTX-35 Phase 1 Clinical Heat Biologics Neoplasms Details

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