DR3 / TNFRSF25 Protein - ACROBiosystems

Home
Products

products by category

Recombinant proteins
GMP Grade CytokinesNew Fc receptor proteins FcRn Proteins IgG Fc Proteins (Isotype Control) CGT development solutions New Targets of CAR-T cell therapy New Generation Tools for CAR DetectionStar Staining FDA DMF filed proteins Multi-pass TpsHot Immune checkpoint proteins ADC targets BsAb targets TME pathway targets CytokinesHot Enzymes Llama IgG Fc fusion protein Biosimilar drug targets Biomarkers & CD antigens All recombinant proteins

Antibodies
Anti-idiotypic antibody Anti-FMC63 mAb Neutralizing antibodies
Kits/Beads
Pre-coupling magnetic beads Inhinitor screening kits ELISA Assay Kits for Quantitative analysis of therapeutic antibodies in serum
Supports on COVID-19 R&DHot
SARS-CoV-2 related products SARS-CoV-2 mutant products SARS-CoV-2 related kits Reagents for vaccine development Reagents for diagnostic development

Featured products

Pre-labeled proteins
New Generation Tools for CAR DetectionStar Staining Biotinylated protein collection FITC & PE labeled proteins
Full-length multi-pass TpsHot
Multi-pass Tps Claudin 18.2 GPCRs CD20 proteins
Proteins for Neuroscience
Proteins for Neuroscience New
Cytokines
ActiveMax Cytokines Hot Promising Therapeutic Targets Hot

Hot targets
CD19 BCMA CD3 proteins IL-2 receptors IL-6 and IL-6 Receptor Proteins Claudin 18.2 GPCRs CD20 proteins CD39/CD73 proteins B7 families TNFSF proteins VEGF proteins PD1 proteins TIGIT Siglec-15 proteins Integrin CD24&siglec-10
Services

Innovation Lab
SPR /BLI analytical serviceNew Enzyme-Linked Immunosorbent Assay (ELISA) Service New Meso Scale Discovery (MSD) ServiceNew Anti-Idiotypic Antibody Development ServiceNew Pseudovirus Neutralization Assay ServiceNew

Licensing Opportunities
Target 4-1BB monoclonal antibody New PD-1/CD80 bispecific antibodyNew Antagonizing TSP1/CD36 Polypeptide Blocking the activation of TGF-β1New Anti-PD-L1 / TIGIT bispecific antibodyNew TIGIT-Fc proteinNew Novel small molecule drug for cancer cachexiaNew
Supports

How to Order Shipping & Payments Global Distributors Testimonials FAQs Download COA
Applications

The Process of How SARS-CoV-2 Infects the Host Quantitative Analysis of mAb in Serum Evaluation of CAR Expression Claudin18.2-VLP：designed for CAR detection SPR & BLI：Binding activity assay SEC-MALS: Aggregation state and purity
News

News Insights Promotions Exhibitions
Resources

Download Brochures Download E-resources Download COA
ACROBiosystems

About Us Join Us Contact Us

DR3 / TNFRSF25

Brief Information

Name:Tumor necrosis factor receptor superfamily member 25
Target Synonym:Apo-3,Apoptosis-inducing receptor AIR,Apoptosis-mediating receptor DR3,Apoptosis-mediating receptor TRAMP,Death receptor 3,Lymphocyte-associated receptor of death,Protein WSL,DDR3,Death Receptor Beta,TNFRSF12,TRAMP,DR3,WSL-1,PH Domain-Containing Family G Member 5,PLEKHG5,WSL-LR,WSL1,APO3,WSL,TR3,TNF Receptor Superfamily Member 25,Death Domain Receptor 3 Soluble Form,GEF720,Guanine Nucleotide Exchange Factor 720,Apoptosis Inducing Receptor,Tumor Necrosis Factor Receptor Superfamily, Member 25,Ple

Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 1 Clinical


TN5-H52H3	Human	Human DR3 / TNFRSF25 Protein, His Tag
TN5-C5257	Cynomolgus	Cynomolgus DR3 / TNFRSF25 Protein, Fc Tag
TN5-H5258	Human	Human DR3 / TNFRSF25 Protein, Fc Tag

Cat. No.

Species

Product Description

Structure

Purity

Feature

TN5-H52H3

Human

Human DR3 / TNFRSF25 Protein, His Tag

TN5-C5257

Cynomolgus

Cynomolgus DR3 / TNFRSF25 Protein, Fc Tag

TN5-H5258

Human

Human DR3 / TNFRSF25 Protein, Fc Tag

Synonym Name

TNFRSF25,DR3,APO3,DDR3,TNFRSF12,WSL,WSL1

Background

Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) is also known as Apo-3, Death receptor 3 (DDR3 or DR3), Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor TRAMP, Lymphocyte-associated receptor of death, Apo-3, which is a member of the TNF-receptor superfamily. TNFRSF25 is a homodimer protein, which can Interact strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. TNFRSF25 is receptor for TNFSF12 / APO3L / TWEAK.

Clinical and Translational Updates

Clinical Drug Information