The 6th Annual Frontiers in Therapeutics and Diagnostics (FTD) Forum

ACROBiosystems is proud to sponsor and present at “The 6th Annual Frontiers in Therapeutics and Diagnostics (FTD) Forum”!

The 6th FTD Forum will cover the latest progress in AI-assisted drug discovery and the recent development of nucleotide-based therapeutics and diagnostics. This year the Forum will be in a virtual format with several concurrent breakout sessions covering the hottest topics in ADC. spatial-genomics, synthetic lethality, wearable medical devices, etc. The audience will have great opportunities to ask questions, share ideas, learn from the experts, and network with their peers. ACROBiosystems is looking forward to meet and connect with you!

ACROBio’s talk: 

Time: 11:15 AM - 12:45 PM PDT.

Topic: ADC and bispecific antibody therapeutics

Title: “Engineering Bispecific Antibody Targets for Novel Arsenal in Immune Therapy”

Speaker: Nicholas J. Abuid, Ph.D, Application Scientist, ACROBiosystems

Abstract: Bispecific antibodies refer to a large family of molecules that recognize two different epitopes or antigens. There has been rising interest in therapeutic applications of these dual-target functionality antibodies. The potential of bispecific antibodies in precisely targeting immune cells with synergistic therapeutic effect on tumor cells stands out among antibody therapeutics in tumor immunotherapy. Bispecific antibodies can bind to two different sites, blocking two separate signaling pathways, enhancing cancer cell cytotoxicity, and reducing drug resistance caused by tumor pathway activation. After binding to two different cell surface antigens, the binding specificity increases. A well-known bispecific antibody target is CD3, which stabilizes T cell receptor structure and induces activating signals. This talk will cover ACROBiosystems’ efforts to engineer and evaluate homogenous CD3 proteins to accelerate the research and development of bispecific antibodies. In addition, our collaborators efforts in bispecific antibody advances will be reviewed.

Meet the speakers