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Your Position: Home > All Other Proteins > Vasorin > Human VASN /Vasorin Protein

Human Vasorin / VASN Protein

  • Synonym
    VASN,SLITL2,Vasorin
  • Source
    Human Vasorin, His Tag (VAN-H52H3) is expressed from human 293 cells (HEK293). It contains AA Cys 24 - Pro 575 (Accession # AAH68575).
    Predicted N-terminus: Cys 24
  • Molecular Characterization
    Vasorin(Cys 24 - Pro 575) AAH68575

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 61.6 kDa. The protein migrates as 80-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    No activity loss is observed after storage at:

    1. 4-8°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Human Vasorin, His Tag (Cat. No. VAN-H52H3) SDS-PAGE gel

Human Vasorin, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

  • Background
    Vasorin (VASN),a single-pass type I membrane protein, is also known as protein slit-like 2 and SLITL2, which contains one EGF-like domain, ten LRR (leucine-rich) repeats, one LRRCT domain and one LRRNT domain. VASN is expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. VASN can interact selectively and non-covalently with TGF-beta, transform growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types. In general, VASN may act as an inhibitor of TGF-beta signaling.
  • References
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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