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Your Position: Home > Bio-Markers & CD Antigens > Carbonic Anhydrase XIV > Human Carbonic Anhydrase XIV /CA14 Protein

Human Carbonic Anhydrase XIV / CA14 Protein

  • Synonym
  • Source
    Human Carbonic Anhydrase XIV, His Tag (CA4-H5227) is expressed from human 293 cells (HEK293). It contains AA Ala 16 - Met 290 (Accession # AAH34412).
    Predicted N-terminus: Ala 16
  • Molecular Characterization
    CA14(Ala 16 - Met 290) AAH34412

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 31.6 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    No activity loss is observed after storage at:

    1. 4-8°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
Human Carbonic Anhydrase XIV, His Tag (Cat. No. CA4-H5227) SDS-PAGE gel

Human Carbonic Anhydrase XIV, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

  • Background
    Carbonic anhydrase XIV (CA14),a member of the alpha-carbonic anhydrase family, is also known as carbonate dehydratase XIV, which is a single-pass type I membrane protein. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. CA14 shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles. As for tissue specificity,CA14 is high expressed in all parts of the central nervous system and lower expressed in adult liver, heart, small intestine, colon, kidney, urinary bladder and skeletal muscle.
  • References
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $290.00

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