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Your Position: Home > Protein > OX40 > OX0-C5251

Cynomolgus / Rhesus macaque OX40 / TNFRSF4 / CD134 Protein, Fc Tag

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  • Synonym
    TNFRSF4,OX40,CD134,OX40L receptor,ACT35,TXGP1L
  • Source
    Cynomolgus / Rhesus macaque OX40, Fc Tag (OX0-C5251) is expressed from human 293 cells (HEK293). It contains AA Lys 28 - Ala 214 (Accession # XP_001090870.1 ). In the region Lys 28 - Ala 214, the AA sequence of Cynomolgus and Rhesus macaque OX40 are homologus.
    Predicted N-terminus: Lys 28
  • Molecular Characterization
    OX40 Structure

    This protein carries a human IgG1 Fc tag at the C-terminus

    The protein has a calculated MW of 46.9 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
OX40 SDS-PAGE

Cynomolgus / Rhesus macaque OX40, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

Bioactivity-ELISA
 OX40 ELISA

Immobilized Human OX40 Ligand, His Tag (active trimer) (Cat. No. OXL-H52Q8) at 5 μg/mL (100 μL/well) can bind Cynomolgus / Rhesus macaque OX40, Fc Tag (Cat. No. OX0-C5251) with a linear range of 0.2-3 ng/mL (QC tested).

  • Background
    Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) is also known as ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, CD antigen CD134, OX40. OX40 / TNFRSF4 contains four TNFR-Cys repeats. TNFRSF4 is receptor for TNFSF4 / OX40L / GP34 and can interacts with TRAF2, TRAF3 and TRAF5.
  • Clinical and Translational Updates

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Price(USD) : $250.00

Price(USD) : $1650.00

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Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:27 Details
  • Latest Research Phase:Phase 3 Clinical

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