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Your Position: Home > Immune Checkpoint Proteins > Recombinant Human CD160 / BY55 Protein

Human CD160 Protein

  • Synonym
    CD160,BY55,NK1,NK28
  • Source
    Human CD160, His Tag (BY5-H5229) is expressed from human 293 cells (HEK293). It contains AA Ile 27 - Ser 159 (Accession # AAH14465).
    Predicted N-terminus: Ile 27
  • Molecular Characterization
    CD160(Ile 27 - Ser 159) AAH14465

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 16.7 kDa. The protein migrates as 25-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    No activity loss is observed after storage at:

    1. 4-8°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Human CD160, His Tag (Cat. No. BY5-H5229) SDS-PAGE gel

Human CD160, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

Bioactivity
Human CD160, His TagHuman CD160, His Tag (Cat. No. BY5-H5229) ELISA bioactivity

Immobilized Human HVEM, Strep Tag (Cat. No. HVM-H5283) at 10μg/mL (100 μL/well) can bind Human CD160, His Tag (Cat. No. BY5-H5229) with a linear range of 0.2-1.3 μg/mL (QC tested).

  • Background
    CD160 antigen is also known as natural killer cell receptor BY55, is a 27 kDa glycoprotein, contains 1 Ig-like V-type (immunoglobulin-like) domain. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. When expressed on vascular endothelial cells, CD160 propagates anti-angiogenic signals and promotes apoptosis.
  • References
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $1800.00

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