>Integrin alpha 4 beta 7
>Human Integrin alpha 4 beta 7 (ITGA4&ITGB7) Heterodimer Protein
Human ITGA4 & ITGB7 Heterodimer Protein, produced by co-expression of ITGA4 and ITGB7, has a calculated MW of 111.4 kDa (ITGA4) & 81.8 kDa (ITGB7). Subunit ITGA4 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB7 contains no tag but a basic tail at the C-terminus. The predicted N-terminus is Tyr 34 (ITGA4) & Glu 20 (ITGB7). The reducing (R) protein migrates as 60-80 kDa (ITGA4) and 105-115 kDa and 130 kDa (ITGB7) respectively due to glycosylation.
>90% as determined by SDS-PAGE.
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM NaCl, pH8.0. Normally trehalose is added as protectant before lyophilization.
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Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
No activity loss is observed after storage at:
Human ITGA4 & ITGB7 on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Natalizumab at 1 μg/mL (100 μL/well) can bind Human ITGA4 & ITGB7 (Cat. No. IT7-H52W4) with a linear range of 8-125 ng/mL (QC tested).
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Price(USD) : $410.00
Price(USD) : $2880.00
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