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Your Position: Home > All Other Proteins > Integrin alpha 11 beta 1 > Human Integrin alpha 11 beta 1 (ITGA11 & ITGB1) Heterodimer Protein

Human Integrin alpha 11 beta 1 (ITGA11 & ITGB1) Heterodimer Protein

  • Synonym
    Integrin alpha 11 beta 1,ITGA11&ITGB1
  • Source
    Human ITGA11 & ITGB1 Heterodimer Protein (IT1-H52W3) is expressed from human 293 cells (HEK293). It contains AA Phe 23 - Pro 1141 (ITGA11) & Gln 21-Asp 728 (ITGB1) (Accession # Q9UKX5-1 (L524R) (ITGA11) & P05556-1 (ITGB1)).
    Predicted N-terminus: Phe 23 (ITGA11) & Gln 21 (ITGB1)
  • Molecular Characterization
    ITGA11&ITGB1(Phe 23 - Pro 1141 (ITGA11) & Gln 21-Asp 728 (ITGB1)) Q9UKX5-1 (L524R) (ITGA11) & P05556-1 (ITGB1)

    Human ITGA11 & ITGB1 Heterodimer Protein, produced by co-expression of ITGA11 and ITGB1, has a calculated MW of 131.6 kDa (ITGA11) & 82.7 kDa (ITGB1). Subunit ITGA11 is  fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus. The protein migrates as 130 kDa (ITGA11) and 100 kDa (ITGB1) under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    No activity loss was observed after storage at:

    1. 4-8°C for 12 months in lyophilized state;

    2. -70°C for 3 months under sterile conditions after reconstitution.

SDS-PAGE
Human ITGA11 & ITGB1 Heterodimer Protein (Cat. No. IT1-H52W3) SDS-PAGE gel

Human ITGA11 & ITGB1 Heterodimer Protein on SDS-PAGE  under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

Bioactivity-ELISA
Human ITGA11 & ITGB1 Heterodimer ProteinHuman ITGA11 & ITGB1 Heterodimer Protein (Cat. No. IT1-H52W3) ELISA bioactivity

Immobilized Native Human Collagen I protein at 2 μg/mL (100 μL/well) can bind Human ITGA11 & ITGB1  Heterodimer Protein (Cat. No. IT1-H52W3) with a linear range of 0.156-2.5 μg/mL (QC tested).

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Price(USD) : $410.00

Price(USD) : $2880.00

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