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Your Position: Home > All Other Proteins > PVRIG > Human PVRIG Protein, Mouse IgG2a Fc Tag, low endotoxin

Human PVRIG Protein, Mouse IgG2a Fc Tag, low endotoxin

  • Synonym
    C7orf15,C7orf15MGC138295,CD112R,MGC104322,MGC138297,MGC2463,PVRIG,CD112 receptor
  • Source
    Human PVRIG, Mouse IgG2a Fc Tag, low endotoxin (PVG-H5253) is expressed from human 293 cells (HEK293). It contains AA Thr 41 - Asp 171 (Accession # Q6DKI7-1).
    Predicted N-terminus: Thr 41
  • Molecular Characterization
    PVRIG(Thr 41 - Asp 171) Q6DKI7-1

    This protein carries a mouse IgG2a Fc tag at the C-terminus.

    The protein has a calculated MW of 40.6 kDa. The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 0.1 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    No activity loss was observed after storage at:

    1. 4-8°C for 12 months in lyophilized state;

    2. -70°C for 3 months under sterile conditions after reconstitution.

SDS-PAGE
Human PVRIG, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. PVG-H5253) SDS-PAGE gel

Human PVRIG, Mouse IgG2a Fc Tag, low endotoxin on SDS-PAGE  under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

Bioactivity-ELISA
Human PVRIG, Mouse IgG2a Fc Tag, low endotoxinHuman PVRIG, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. PVG-H5253) ELISA bioactivity

Immobilized Human Nectin-2, Fc Tag (Cat. No. PV2-H5253) at 5 μg/mL (100 μL/well) can bind Human PVRIG, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. PVG-H5253) with a linear range of 1-31 ng/mL (QC tested).

  • Background
    Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.
  • References
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $350.00

Price(USD) : $2310.00

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