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Your Position: Home > Immune Checkpoint Proteins > ICOS > ICS-H52H6

Human ICOS / CD278 (C136S, C137S) Protein, His Tag

  • Synonym
    ICOS,CD278,AILIM,Inducible T-cell costimulator
  • Source
    Human ICOS (C136S, C137S), His Tag (ICS-H52H6) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Phe 141 (Accession # Q9Y6W8-1 (C136S, C137S)).
    Predicted N-terminus: Glu 21
  • Molecular Characterization
    Online(Glu 21 - Phe 141) Q9Y6W8-1 (C136S, C137S)

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 15.2 kDa. The protein migrates as 23-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >85% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Human ICOS (C136S, C137S), His Tag (Cat. No. ICS-H52H6) SDS-PAGE gel

Human ICOS (C136S, C137S), His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 85%.

Bioactivity-ELISA
Human ICOS (C136S, C137S), His TagHuman ICOS (C136S, C137S), His Tag (Cat. No. ICS-H52H6) ELISA bioactivity

Immobilized Human B7-H2, Fc Tag (Cat. No. B72-H5254) at 1 μg/mL (100 μL/well) can bind Human ICOS (C136S, C137S), His Tag (Cat. No. ICS-H52H6) with a linear range of 0.008-0.125 μg/mL (QC tested).

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Price(USD) : $350.00

Price(USD) : $2400.00

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  • Number of Drugs in Clinical Trials:6 Details
  • Latest Research Phase:Phase ?

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DMF (Drug Master File)

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