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Your Position: Home > Receptor Tyrosine Kinases > Axl > AXL-R52H7

Rhesus macaque Axl Protein, His Tag

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  • Synonym
    AXL,UFO
  • Source
    Rhesus macaque Axl, His Tag (AXL-R52H7) is expressed from human 293 cells (HEK293). It contains AA Glu 33 - Pro 449 (Accession # XP_014979499.1).
    Predicted N-terminus: Glu 33
  • Molecular Characterization
    Online-Res(Glu 33 - Pro 449) XP_014979499.1

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 47.1 kDa.

  • Endotoxin
  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    No activity loss was observed after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    AXL Receptor Tyrosine Kinase is also known as Tyrosine-protein kinase receptor UFO, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily. AXL contains two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain. AXL is highly expressed in metastatic colon tumors. AXL is activated by GAS6-binding and subsequent autophosphorylation. AXL is involved in signal transduction from the extracellular matrix into the cytoplasm by binding growth factors, and thus implicated in the stimulation of cell proliferation.
  • References
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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