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Your Position: Home > Fc Receptor Proteins > FcRn (FCGRT & B2M) > FCM-R52W5

Rabbit FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Tag Free (SPR verified)

  • Synonym
    FcRn,FCGRT & B2M
  • Source
    Rabbit FCGRT&B2M Heterodimer Protein, His Tag&Tag Free (SPR verified) (FCM-R52W5) is expressed from human 293 cells (HEK293). It contains AA Ala 24 - Val 297 (FCGRT) & Val 22 - Tyr 120 (B2M) (Accession # ABY47597.1(FCGRT) & ALR85722.1(B2M)).
    Predicted N-terminus: Ala 24 (FCGRT) & Val 22 (B2M)
  • Molecular Characterization
    Online(Ala 24 - Val 297 (FCGRT) & Val 22 - Tyr 120 (B2M)) ABY47597.1 (FCGRT) & ALR85722.1 (B2M)

    Rabbit FCGRT&B2M Heterodimer Protein, His Tag&Tag Free, produced by co-expression of FCGRT and B2M, has a calculated MW of 32.1 kDa (FCGRT) and 11.7 kDa (B2M). Subunit FCGRT is fused with a polyhistidine tag at the C-terminus and subunit Beta-2 microglobulin (B2M) contains no tag at the C-terminus. The reducing (R) protein migrates as 34 kDa (FCGRT) and 12 kDa (B2M) respectively due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Rabbit FCGRT&B2M Heterodimer Protein, His Tag&Tag Free (SPR verified) (Cat. No. FCM-R52W5) SDS-PAGE gel

Rabbit FCGRT&B2M Heterodimer Protein, His Tag&Tag Free (SPR verified) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Bioactivity-SPR
Human_FcRn_Heterodimer_Protein_SPR

Rabbit FCGRT&B2M Heterodimer Protein, His Tag&Tag Free (Cat. No. FCM-R52W5) captured on CM5 Chip via anti-His antibody can bind Herceptin® with an affinity constant of 2.12 μM as determined in SPR assay (Biacore T200) (QC tested).

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Price(USD) : $350.00

Price(USD) : $2600.00

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