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Your Position: Home > Recombinant Proteins > S protein RBD > SPD-M141

Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgM (AM130)

  • Source
    Anti-SARS-CoV-2 Spike RBD Antibody, Human IgM (SPD-M141) is a chimeric monoclonal antibody combining the constant domains of the human IgM molecule with mouse variable regions.
  • Isotype
    Human IgM | Kappa
  • Specificity
    This product is a specific antibody against SARS-CoV-2 Spike Protein RBD domain. The cross-reactivity with other coronaviruses has not been tested yet.
  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 . Normally trehalose is added as protectant before lyophilization.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20 to -70°C for 12 months in lyophilized state from date of receipt;
    2. -70°C for 3 months under sterile conditions after reconstitution.
Bioactivity-ELISA
Anti-SARS-CoV-2 Spike RBD Antibody, Human IgMAnti-SARS-CoV-2 Spike RBD Antibody, Human IgM (Cat. No. SPD-M141) ELISA bioactivity

Immobilized Anti-SARS-CoV-2 Spike RBD Antibody, Human IgM (Cat. No. SPD-M141) at 2 μg/mL (100 μL/well) can bind SARS-CoV-2 S protein (R683A, R685A), His Tag, Super stable trimer (Cat. No. SPN-C52H9) with a linear range of 2-39 ng/mL (QC tested).

Anti-SARS-CoV-2 Spike RBD Antibody, Human IgMAnti-SARS-CoV-2 Spike RBD Antibody, Human IgM (Cat. No. SPD-M141) ELISA bioactivity

Immobilized Anti-Human IgM Antibody, Mouse IgG1 at 5 μg/mL (100 μL/well), add increasing Anti-SARS-CoV-2 Spike RBD Antibody, Human IgM (Cat. No. SPD-M141) diluted in 10% Human serum. Detection was performed using HRP-conjugated SARS-CoV-2 S protein RBD with sensitivity of 10 ng/mL (QC tested).

  • Background
    It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
  • References
    • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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    Order Details

    Price(USD) : $380.00

    Price(USD) : $2500.00

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    DMF (Drug Master File)

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