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Your Position: Home > All Other Proteins > TIM-1 > KI1-H52H3

Human TIM-1 / HAVCR1 Protein, His Tag (MALS verified)

  • Synonym
    HAVCR1,KIM1,TIM1,TIMD1
  • Source
    Human TIM-1 / HAVCR1, His Tag (KI1-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ser 21 - Gly 295 (Accession # Q96D42-1).
  • Molecular Characterization
    Online(Ser 21 - Gly 295) Q96D42-1

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 31.5 kDa. The protein migrates as 60-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Human TIM-1 / HAVCR1, His Tag (Cat. No. KI1-H52H3) SDS-PAGE gel

Human TIM-1 / HAVCR1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

SEC-MALS
Human TIM-1 / HAVCR1, His Tag (Cat. No. ) MALS images

The purity of (Cat. No. KI1-H5257) was more than 90% and the molecular weight of this protein is around 55-70 kDa verified by SEC-MALS.

  • Background
    Hepatitis A virus cellular receptor 1 is also known as HAVCR1, HAVCR, KIM1, TIM, TIM1, TIMD1, is widely expressed with highest levels in kidney and testis. The protein encoded by HAVCR1 gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene. HAVCR1 may play a role in T-helper cell development, the regulation of asthma and allergic diseases and in kidney injury and repair. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $350.00

Price(USD) : $2310.00

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