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Your Position: Home > All Other Proteins > LSECtin > CLG-H52H3

Human LSECtin / CLEC4G Protein, His Tag

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  • Synonym
    CLEC4G,LSECtin
  • Source
    Human LSECtin, His Tag (CLG-H52H3) is expressed from human 293 cells (HEK293). It contains AA Lys 55 - Cys 293 (Accession # Q6UXB4-1).
    Predicted N-terminus: Lys 55
  • Molecular Characterization
    Online-Res(Lys 55 - Cys 293) Q6UXB4-1

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 28.4 kDa.

  • Endotoxin
  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    C-type lectin superfamily 4, member G (CLEC4G) is also known as liver and lymph node sinusoidal endothelial cell C-type lectin (LSECtin), which is a member of subgroup II of the C-type (Ca2+-dependent) lectin superfamily. CLEC4G / LSECtin binds to mannose, GlcNAc, and fucose in a Ca2+-dependent manner. In addition, CLEC4G / LSECtin has the ability to bind to surface glycoproteins of enveloped viruses. In particular, interaction of LSECtin with the surface glycoproteins of severe acute respiratory syndrome (SARS) coronavirus and Ebola virus has been described, and LSECtin-mediated infection of cells by Ebola virus has been demonstrated.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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