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Your Position: Home > TME Relevant Pathway > FGF-7 > FG7-H52H5

Human FGF-7 / HBGF-7 / KGF Protein, His Tag (HPLC & SPR verified)

  • Synonym
    FGF-7,Fibroblast growth factor 7,HBGF-7,Keratinocyte growth factor,KGF
  • Source
    Human FGF-7, His Tag(FG7-H52H5) is expressed from human 293 cells (HEK293). It contains AA Cys 32 - Thr 194 (Accession # P21781-1 ).
    Predicted N-terminus: Cys 32
  • Molecular Characterization
    FGF-7 Structure

    This protein carries a polyhistidine tag at the C-terminus

    The protein has a calculated MW of 20.8 kDa. The protein migrates as 25-27 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

    >95% as determined by SEC-HPLC.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
FGF-7 SDS-PAGE

Human FGF-7, His Tag on SDS-PAGE under non-reducing (NR) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-HPLC
FGF-7 SEC-HPLC

The purity of Human FGF-7, His Tag (Cat. No. FG7-H52H5) was greater than 95% as determined by SEC-HPLC.

Bioactivity-SPR
 FGF-7 SPR

Human FGF R2 (IIIb), Fc Tag (Cat. No. FGB-H5256) immobilized on CM5 Chip can bind Human FGF-7, His Tag (Cat. No. GCR-H82E3) with an affinity constant of 0.275 μM as determined in a SPR assay (Biacore 8K) (QC tested).

  • Background
    Fibroblast growth factor (FGF) 7 (is also known as Keratinocyte growth factor (KGF)), a member of FGF family, is initially found to be secreted from mesenchymal cells to repair epithelial tissues. As a well-characterized paracrine growth factor for tissue growth and regeneration, fibroblast growth factor 7 (FGF7) is involved in a number of physiological and pathological processes, including lung disease and cancer. The stromal-derived FGFs, such as FGF7 and FGF10, control epithelial cell resident FGFR2IIIb activities, promote net tissue homeostasis, and restraint tumor cells from progression to malignancy.
  • Clinical and Translational Updates
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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ETD of in-stock products: 2 business days

Price(USD) : $350.00

Price(USD) : $2310.00

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