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Your Position: Home > Cytokines > FGF-22 > FG2-H5246

Human FGF-22 Protein, His Tag

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  • Synonym
    FGF-22,Fibroblast growth factor 22
  • Source
    Human FGF-22, His Tag (FG2-H5246) is expressed from human 293 cells (HEK293). It contains AA Thr 23 - Ser 170 (Accession # Q9HCT0-1).
    Predicted N-terminus: His
  • Molecular Characterization
    Online-Res(Thr 23 - Ser 170) Q9HCT0-1

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 19.2 kDa.

  • Endotoxin
  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    The FGF7 subfamily, consisting of FGF3, FGF7, FGF10, and FGF22, is unique among FGFs in that its members are secreted exclusively by the mesenchyme, and specifically activate the “b” isoforms of FGFR1 (FGFR1b) and FGFR2 (FGFR2b) present in the overlying epithelium. FGF 22 is secreted from cerebellar granule cells to recruit axons projected from pontine and vestibular neurons expressing FGFR 2b. FGF 22-FGFR 2b signaling organizes synapse formation by inducing axon projection toward FGF 22 secreting cells.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $350.00

Price(USD) : $2310.00

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