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Your Position: Home > Cytokines > FGF-10 > FG0-H5245

Human FGF-10 / KGF 2 Protein, His Tag

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  • Synonym
    FGF-10,Fibroblast growth factor 10,Keratinocyte growth factor 2
  • Source
    Human FGF-10, His Tag (FG0-H5245) is expressed from human 293 cells (HEK293). It contains AA Gln 38 - Ser 208 (Accession # O15520-1).
    Predicted N-terminus: His
  • Molecular Characterization
    Online-Res(Gln 38 - Ser 208) O15520-1

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 21.2 kDa.

  • Endotoxin
  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    Fibroblast Growth Factor 10 (FGF 10) is an evolutionary conserved secreted growth factor mediating mostly mesenchymal to epithelial signaling. FGF 10 belongs to the FGF 7 subfamily and shares similar biochemical and amino acid sequences with its constituent members (FGF3, FGF 7 and FGF 22). As a paracrine FGF, FGF 10 elicits its biological responses by activating the fibroblast growth factor receptor 2b (FGF R 2b), is crucial for governing proximal distal outgrowth as well as patterning and acts upstream of the known apical ectodermal ridge (AER) marker FGF 8. FGF10 is also implicated in pancreatic cancer, and that overexpression of FGFR2b is associated with metastatic invasion.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $350.00

Price(USD) : $2310.00

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